Host-targeted Therapeutics

Antimicrobial Resistance:


-Most published papers provide evidence to support limiting use of antibiotics in agriculture (Tackling drug-resistance infections globally: Final report and recommendations)

-Poor infection control contributes to increased resistance and loss of life (Infection prevention, control and surveillance: Limiting the development and spread of drug resistance)


-70% of all antibiotics are consumed by animals (Antimicrobials in agriculture and the environment: Reducing unnecessary use and waste)

-Counterfeits and substandard antimicrobial drugs threaten public health (Safe, secure and controlled: Managing the supply chain of antimicrobials)

-Out of 40 million patients, 27 million receive antibiotics unnecessarily (Rapid Diagnostics: Stopping unnecessary use of antibiotics)

-It takes 23 years to achieve profit from antibiotics sale (Securing new drugs for future generations, The Pipeline of antibiotics)

-Taking actions (Tackling a global health crisis: Initial steps)

-Grant funding at early stages will drive the development of novel antimicrobials (Survey of actors involved in the development of antimicrobials)


-Over ten million people will die from AMR by 2050 (UK: The Review on Antimicrobial Resistance, Jim O’Neill)


-“…the ignorant man may easily underdose himself and by exposing his microbes to non-lethal quantities of the drug make them resistant.” – Alexander Fleming, Nobel Prize Lecture. December 11, 1945